ea0049ep1356 | Thyroid (non-cancer) | ECE2017
Tavares Patricia
, Machado Catarina
, Pedroso Jose Carlos
, Vieira Joana
, Rocha Gustavo
, Monteiro Sara
, Sousa Ana Margarida
, Rodrigues Pedro
, Lira Agostinho
, Oliveira Maria Joao
Introduction: GravesÂ’ disease (GD) hyperthyroidism is caused by autoantibodies against TSH receptor (TRAb). Three varieties of TRAb are now recognized: stimulating (TSI), blocking and neutral antibodies. Current TRAb immunoassays detect and quantify serum immunoglobulins that interact with the TSH receptor but without discriminating their function. An automated immunoassay for the detection and quantification of TSI is available.Objective: Our study...